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According to a report in the December 2009 print issue of the Journal of Leukocyte Biology, breaking the nervous-immune systems link might lead to new treatments for a wide range of autoimmune disorders like lupus, arthritis, and eczema under control.
That’s because researchers from the University of Connecticut Health Center have found that the same part of our nervous system that is responsible for the fight-or-flight response (called the sympathetic nervous system) also controls regulatory T cells, which are used by the body to end an immune response once a foreign invader has been removed or destroyed.
“We show for the first time that the nervous system controls the central immune police cells, called regulatory T cells,” said Robert E. Cone, Ph.D., a senior researcher in whose laboratory the work was done at the University of Connecticut Health Center.
The expert added: “This further shows that it is imperative to concentrate on the neuro-immune interactions and to understand how these two different systems, the immune and nervous systems, interact.”
To reach the conclusion, Cone, Sourojit Bhowmick and colleagues injected some mice with a drug called 6-hyroxydopamine (6-OHDA) that selectively removes sympathetic nerves located in different organs, or a saline solution. Mice injected with 6-OHDA, which effectively severed the link between the nervous system and the immune system had twice as many regulatory T cells as the control group in their spleens and lymph nodes.
Further analysis showed that the increase in regulatory T cells resulted from an increase in a protein called “TGF-beta,” which directs the development and survival of regulatory T cells.
With this information in hand, Cone and colleagues then sought to see if 6-OHDA would prevent autoimmune disorders from developing. To do this, they injected 6-OHDA or a saline solution into mice before subjecting them and a control group to conditions known to cause an autoimmune disease similar to multiple sclerosis in humans.
The data from the Office for National Statistics reveals that over 120,000 women secured new part-time jobs in the last quarter, while 50,000 men were forced to roam about jobless, reports the Daily Star .
British women have been largely finding employment in education and health sectors, where the personnel have actually increased in the last quarter.
And with thousands made redundant by the construction industry, the current number of employed men in Britain is the lowest in the last ten years.
American economists coined the term “mancession”, where men were facing four fifths of all job losses.
A British grandmother, who was sterilised twice 13-years-ago, has given birth to a ‘miracle’ babyboy. Debbie Amos, 43, had the operation to stop her falling pregnant
Amos, a resident of Colchester, Essex, said: “At the end of July, I started feeling tired and then felt movements in my stomach.
“I thought I could feel something – I thought it was wind at first but I was tired as well so I thought I better do a test. When she did a pregnancy test, she could not believe that she was six months pregnant.
“I didn’t really believe it until he came out,” she said. She took fertility drug Clomid to speed up ovulation when she was 19 which helped her get pregnant with daughter Kerri, who is now 24 and a mother.
Two years later, she conceived her first son Glen, who is now 19, and again with a daughter four years later.
To ensure no more pregnancies, she underwent double sterilisation at Colchester General Hospital. again after having her first three children. But three-months-ago she felt strange movements in her stomach and a test revealed she was six months pregnant. Now she is mother to health baby boy Connor, born last week, who is younger than her grandchildren, The Daily Mail reported.